Sensing with Ion Channels

Acid sensing ion channels (ASICs) are widely expressed in central and peripheral nervous system. They are involved in a variety of physiological and pathophysiological processes: synaptic transmission, learning and memory, pain perception, ischemia, etc. During ischemia, metabolic acidosis causes th …
22/02/2016 · Gating charges in voltage-sensing domains (VSD) of voltage-sensitive ion channels and enzymes are carried on arginine side chains rather than lysine. This arginine preference may result from the ...
15/01/2019 · TRPV1. TRPV1, also known as the capsaicin receptor, is a polymodal, nonselective cation channel expressed by all major classes of nociceptive neurons and is important for the detection of noxious stimuli (Vay et al., 2012; Caterina, 2014).Ion channels, including TRPV1, are typically found in the plasma membrane and form a passageway from one side of the …
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk Nat Commun. 2020 Jan 15;11(1):282. doi: 10.1038/s41467-019-14146-6. Authors Lijun Wang 1 ... Ion Channels Piezo1 protein, mouse ...
15/01/2019 · TRPV1. TRPV1, also known as the capsaicin receptor, is a polymodal, nonselective cation channel expressed by all major classes of nociceptive neurons and is important for the detection of noxious stimuli (Vay et al., 2012; Caterina, 2014).Ion channels, including TRPV1, are typically found in the plasma membrane and form a passageway from one side of the …

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